Anticuerpos antiperoxidasa (anti-TPO) y antitiroglobulina (anti-TG) en pacientes con sospecha clínica de tiroiditis de Hashimoto
Anti-thyroid peroxidase (anti-tpo) and anti-thyroglobulin (anti-tg) antibodies in patients with clinical suspicion of hashimoto's thyroiditis
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Gómez Sifontes, Abimael Esaúl
Pino Flores, Oswers Xadier
Osorio Brito, Yoger Daniel
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Bolívar, Venezuela : UBV
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La Tiroiditis de Hashimoto es la enfermedad autoinmunitaria más frecuente que afecta la glándula tiroides, provocando su destrucción progresiva a través de la acción del sistema inmunológico, que produce anticuerpos como anti-TPO y anti-TG. Esta condición afecta la producción hormonal y genera síntomas diversos. Para evaluar la presencia de estos biomarcadores, se llevó a cabo un estudio descriptivo y transversal entre enero y marzo de 2025 con 66 pacientes atendidos en un laboratorio privado. Los resultados mostraron una alta seropositividad, siendo el 36,36 % para anti-TPO y el 25,76 % para anti-TG. La presencia de anti-TPO fue estadísticamente significativa en mujeres, que constituyeron el género predominante, en un rango etario de 28 a 45 años.
Hashimoto's thyroiditis is the most common autoimmune disease affecting the thyroid gland, causing its progressive destruction through the action of the immune system, which produces antibodies such as anti-TPO and anti-TG. This condition affects hormone production and generates various symptoms. To evaluate the presence of these biomarkers, a descriptive, cross-sectional study was conducted between January and March 2025 with 66 patients seen at a private laboratory. The results showed high seropositivity, with 36.36% testing positive for anti-TPO and 25.76% for anti-TG. The presence of anti-TPO was statistically significant in women, who constituted the predominant gender, in the 28-45 age range.
Hashimoto's thyroiditis is the most common autoimmune disease affecting the thyroid gland, causing its progressive destruction through the action of the immune system, which produces antibodies such as anti-TPO and anti-TG. This condition affects hormone production and generates various symptoms. To evaluate the presence of these biomarkers, a descriptive, cross-sectional study was conducted between January and March 2025 with 66 patients seen at a private laboratory. The results showed high seropositivity, with 36.36% testing positive for anti-TPO and 25.76% for anti-TG. The presence of anti-TPO was statistically significant in women, who constituted the predominant gender, in the 28-45 age range.
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TIROIDITIS, FRECUENCIA, SALUD, ENFERMEDAD, GÉNERO, PACIENTES, ESTADÍSTICA, RIESGO
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páginas 10-25
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Gómez Sifontes, Abimael Esaúl, Oswers Xadier Pino Flores y Yoger DanielOsorio Brito. 2026. Anticuerpos antiperoxidasa (anti-TPO) y antitiroglobulina (anti-TG) en pacientes con sospecha clínica de tiroiditis de Hashimoto o Anti-thyroid peroxidase (anti-tpo) and anti-thyroglobulin (anti-tg) antibodies in patients with clinical suspicion of hashimoto's thyroiditis. Orinoco Pensamiento y Praxis. Revista arbitrada de Investigación Social, Diversidad Cultural y Poder Popular (26): 10-25.
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