La producción, el tráfico y el consumo de sustancias psicoactivas ilícitas (SPI) constituyen en los albores del siglo XXI un fenómeno y una problemática de alcance e implicancias globales, con soluciones que aún no se avizoran en el contexto mundial. Indagar sobre el circuito productivo de las SPI resulta una cuestión compleja, multidimensional y de marcada multiescalaridad y multiterritorialidad. El objetivo principal del artículo consiste en evidenciar la multiescalaridad espacial y temporal del circuito de las SPI, determinando el flujo relacional entre lo global y lo local.The production, trafficking and consumption of illicit psychoactive substances (IPS) constitute, at the dawn of the 21st century, a phenomenon and a problem of global scope and implications with solutions that are not yet found. Investigating the productive circuit of CPS is a complex, multidimensional and markedly multiscalar and multiterritorial issue. The main objective of this article is to show the spatial and temporal multiscalarity of the CPS circuit, determining the relational flow between the global and the local. Quantitative and qualitative sources are used, both primary and secondary, to illustrate integrally its causes, its state and its effects at a glocal level.